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For each data run a new panel should be added here, describing the significant functional or data changes in that analysis run. Mike will cut them from here and paste to the public page upon releasing that run

If sparse, do diffs with last analysis run, to see new tasks/data added (and optionally ask team, via email, to verify).  The /wiki/spaces/GDAC/pages/844334194

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titleSpring 2016 Analysis Run

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This is likely to be either the penultimate or perhaps even final standard Firehose analysis run of the TCGA project. Custom AWG runs will continue for TCGA as needed.

Summary of sample changes (see the comprehensive samples report for more details):

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BCR

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+1

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(11368 total)

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Clinical

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+32

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(11196 total)

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CN

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(10987 total)

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MAF

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+313

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(7099 total)

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Methylation

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+1

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(10972 total)

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miRSeq

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+2

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(10156 total)

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mRNASeq

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+164

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(10267 total)

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rawMAF

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+2072

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(6322 total)

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RPPA

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+627

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(7429 total)

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  1. used median filtering in primary APOBEC analysis
  2. in downstream clinical correlations, corrected names of categorical variables and descriptions of how they were utilized

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  1. Modified the p-value calculation of survival analysis with continuous data. It now uses the quantile interval categorical values instead of continuous values.
  2. Previously it had one hazard ratio value for one continuous value, but now has multiple hazard ratio values for quantile interval curves (and are now reflected in the plot legends)

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Panel
titleTasks Under Development
  •  Migrated implementation of our clustering codes away from GenePattern into FH native jobs, consolidating and simplifying along the way (needs more description/tailoring)
  • The spearman correlation was used in the pipeline of Correlate_mRNAseq_vs_Mutation_APOBEC.

 

Table from 2013_09_23 analysis run;  keep until next run is posted which corrects the GAF 3.0 issues

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