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| Acronym/Term | Definition | Notes |
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| 10X | Another sequencing company | https://www.10xgenomics.com/ |
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| Adapter | Allows hybridization to the flow cell, contains molecular barcode index (special sequence of synthesized DNA) |
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| AoU |
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| All of Us |
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| BITS | Broad Information Technology Services | |
| Blacklisting |
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| Similar to "flagging" | ||
| bp |
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| Base pair | ||
| BQMS |
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| Broad Quality Management System. Errors & variation tracking. | ||
| BSP | Biological Samples Platform (obsolete) |
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| BTL | Broad Technology Labs | |
| Buffy coat | A particular layer of centrifuged blood/cell prep |
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| CAPA | Corrective Action Preventative Action - BQMS Issue Type | |
| CCLF | Cancer Cell Line Factory |
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| . Part of the |
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| Cancer group at Broad, |
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| GP LIMS/Analytics team working with them |
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| Cell line |
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| cfDNA |
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| Cell-free DNA | ||
| CI |
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| Continuous Improvement | ||
| CLIA | Clinical Laboratory Improvement Amendments | https://www.aafp.org/practice-management/regulatory/clia.html |
| CMI | Count Me In. Cancer research project | |
CRSP | Clinical Research Sequencing Platform |
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| DCFM | Date Coverage First Met | |
| ExEx | Exome Express |
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| . Special system for faster results turnaround for some exome sequencing products. | |
| FFP / FFPE | Formaline fixed paraffin embedded (Tissue fixed in formaline and paraffin) |
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| https://www.biochain.com/general/what-is-ffpe-tissue/ | |
| GAP | Genomics Analysis Platform. Obsolete group/LIMS at Broad that has been absorbed into Genomics Platform |
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| GPLIM |
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| Jira project for GP LIMS | ||
| GSA |
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| Global Screening Array. A chip type | ||
| HS | Hybrid Selection or High Sensitivity | |
| IDT | A company that synthesizes DNA (e.g. for hybrid selection) | |
| Infinium |
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| Genotyping platform for Illumina | ||
| Insert size | Length of DNA fragments after shearing, before adapter ligation | |
| LC |
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| Library Construction | ||
| LCSET | Library construction set | |
| LIMS | Laboratory Information Management System | |
| Nexome | Exams processed with kits from Nextera? | |
| ORSP |
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| Office of Research Subject Protection | ||
| PCR |
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| Polymerase chain reaction | ||
| PDO |
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| Product Order | ||
| Pico |
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| Pico |
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| -green, a |
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| fluorescent dye used to quant DNA |
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| Pond, bait, etc |
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| . | Hybrid selection terms, hyb sel is a process of creating exomes |
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| Pooling penalty | How similarly represented the different samples are in a pool of samples | |
| Qiagen |
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| Company that makes extraction kits |
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| QTP | Quant Template Pool | |
| RGHQS | Regroup H Quality Scores | |
| RP | Research project | |
| SAWS | Sample Analytics Workflow Service | |
| SNP | Single nucleotide polymorphism | |
| SPRI | Solid Phase Reversible |
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| Immobiization (AMPure by Agencourt) |
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| SQM | ??? The group that does procurement and materials management | |
| SRS | Sample retrieval and storage | |
| TAG | The Analytics Group OR Translational Analysis Group | |
| TDE | Tableau Data Extract | |
| TOPMed | Trans-Omics for Precision Medicine |
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| TSCA | Process used for CCLF samples (among others) | |
| VBGP |
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| Verily Broad Genomics Platform??? |
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| aka "Broad |
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| West" | |
| VVP | Volume verified pipetting. A liquid handler robot from Dynamic Devices |
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| http://dynamicdevices.com/vvp-volume-verified-pipetting/ | ||
| WES (or WEX) | Whole Exome Sequencing | |
| WGS |
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| Whole Genome Sequencing |
| Panel | ||
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Broad Institute Acronyms (external link) /wiki/spaces/DSDEGP/pages/475332729 /wiki/spaces/GAWB/pages/90341450 Broad/Illumina Genome Analyzer Boot Camp (to be viewed for reference about the Genomics Platform) |